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Pregnanediol is a metabolite that results from the breakdown of progesterone, a hormone that plays a crucial role in the menstrual cycle and pregnancy. The measurement of pregnanediol in urine serves as an important indicator of progesterone levels within the body. This test is particularly useful for individuals monitoring their ovulation cycles, as it can be performed at home to detect ovulation. Various factors can influence the levels of pregnanediol in the urine. For instance, adrenocorticotropic hormone (ACTH) can lead to an increase in pregnanediol levels, while the use of oral contraceptives or hormone replacement therapies may result in decreased levels. Additionally, elevated pregnanediol levels can be associated with certain medical conditions, such as ovarian cysts, tumors, adrenocortical hyperplasia, and hyperadrenocorticism. Conversely, decreased levels of pregnanediol may indicate conditions such as amenorrhea, ovarian failure, fetal death, and preeclampsia. Understanding these variations is essential for healthcare professionals when interpreting test results and assessing hormonal health.
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Pregnanediol testing is indicated for various clinical scenarios where monitoring progesterone levels is essential. The following conditions and situations may warrant the measurement of pregnanediol:
The procedure for measuring pregnanediol typically involves the collection of a urine sample, which can be done at home or in a clinical setting. The following steps outline the general process:
After the collection of the urine sample and subsequent analysis, patients may not require any specific post-procedure care. However, it is essential for healthcare providers to discuss the results with the patient, explaining the implications of the pregnanediol levels in relation to their hormonal health. If the results indicate abnormal levels, further evaluation or additional testing may be necessary to determine the underlying cause and appropriate management. Patients should be advised to follow up with their healthcare provider to discuss any concerns or questions regarding their hormonal status and potential treatment options.
| Short Descr | ASSAY OF PREGNANEDIOL | Medium Descr | PREGNANEDIOL | Long Descr | Pregnanediol | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| GA | Waiver of liability statement issued as required by payer policy, individual case | GY | Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit | 91 | Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient. |
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| Pre-1990 | Added | Code added. |
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