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Official Description

Lipase

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83690 refers to the laboratory test for measuring lipase levels in blood and body fluids. Lipase is a crucial enzyme produced by the pancreas, which plays a significant role in the digestion of dietary fats by breaking them down into fatty acids and glycerol. This test is particularly important in diagnosing various medical conditions, as elevated lipase levels can indicate several health issues. Conditions such as small bowel obstruction, celiac disease, cholecystitis, duodenal ulcer, severe gastroenteritis, macrolipasemia, pancreatitis, and pancreatic tumors may lead to increased lipase levels in the body. Additionally, this test may be ordered in cases where there is a family history of lipoprotein lipase deficiency, which can affect lipid metabolism. The procedure involves obtaining a blood sample through venipuncture, which is separately reportable, while other body fluids may be collected using different methods. The analysis of these samples is conducted using quantitative enzymatic methodology, ensuring accurate measurement of lipase levels for diagnostic purposes.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The lipase test (CPT® Code 83690) is indicated for the following conditions:

  • Small Bowel Obstruction - A blockage in the small intestine that can lead to elevated lipase levels.
  • Celiac Disease - An autoimmune disorder where the ingestion of gluten leads to damage in the small intestine, potentially affecting lipase levels.
  • Cholecystitis - Inflammation of the gallbladder, which may cause increased lipase production.
  • Duodenal Ulcer - A sore on the lining of the duodenum that can influence lipase levels.
  • Severe Gastroenteritis - Inflammation of the stomach and intestines that can elevate lipase levels.
  • Macrolipasemia - A condition characterized by high levels of lipase in the blood.
  • Pancreatitis - Inflammation of the pancreas, which is commonly associated with significantly elevated lipase levels.
  • Pancreatic Tumors - Tumors in the pancreas that may lead to abnormal lipase levels.
  • Family History of Lipoprotein Lipase Deficiency - The test may be ordered to assess potential genetic predispositions affecting lipase levels.

2. Procedure

The procedure for conducting the lipase test involves several key steps to ensure accurate results:

  • Step 1: Sample Collection - A blood sample is obtained through venipuncture, which is a standard method for drawing blood. This step is crucial as it provides the primary specimen for testing lipase levels. The venipuncture must be performed by a qualified healthcare professional to ensure the integrity of the sample.
  • Step 2: Collection of Other Body Fluids - In addition to blood, other body fluids may be collected using various methods, depending on the clinical scenario. These fluids can also be tested for lipase levels if indicated.
  • Step 3: Testing Methodology - The collected blood and body fluid samples are analyzed using quantitative enzymatic methodology. This technique allows for precise measurement of lipase levels, providing essential information for diagnosis and treatment planning.

3. Post-Procedure

After the lipase test is performed, there are generally no specific post-procedure care requirements for the patient. However, it is important for healthcare providers to monitor the patient’s condition and interpret the results in the context of clinical findings. Elevated lipase levels may necessitate further diagnostic evaluation or management based on the underlying condition suspected. Patients should be informed about the potential need for follow-up tests or consultations depending on the results of the lipase test.

Short Descr ASSAY OF LIPASE
Medium Descr ASSAY OF LIPASE
Long Descr Lipase
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
X1 Continuous/broad services: for reporting services by clinicians, who provide the principal care for a patient, with no planned endpoint of the relationship; services in this category represent comprehensive care, dealing with the entire scope of patient problems, either directly or in a care coordination role; reporting clinician service examples include, but are not limited to: primary care, and clinicians providing comprehensive care to patients in addition to specialty care
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
Q4 Service for ordering/referring physician qualifies as a service exemption
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
AY Item or service furnished to an esrd patient that is not for the treatment of esrd
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
CR Catastrophe/disaster related
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
KX Requirements specified in the medical policy have been met
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
PN Non-excepted service provided at an off-campus, outpatient, provider-based department of a hospital
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
QW Clia waived test
SA Nurse practitioner rendering service in collaboration with a physician
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
Pre-1990 Added Code added.
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