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Official Description

Androsterone

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82160 refers to a laboratory test specifically designed to measure the levels of androsterone in the body. Androsterone is classified as an endogenous steroid hormone, which means it is naturally produced within the body. It is known for its weak androgenic effects, which are related to male characteristics and reproductive activity. Additionally, androsterone plays a role in modulating GABA receptors, which are critical for inhibitory neurotransmission in the brain, and it possesses anticonvulsive properties that may help in managing seizure disorders. Elevated levels of androsterone can be indicative of certain medical conditions, such as Cushing's syndrome, a disorder characterized by excessive cortisol production. For accurate results, it is essential that patients refrain from taking adrenocorticotropic hormone (ACTH), steroids, and gonadotropins for at least 48 hours prior to the test. The test itself involves obtaining a blood sample through a procedure known as venipuncture, which is separately reportable. The serum or plasma obtained from the blood sample is then analyzed using a technique called radioimmunoassay, a sensitive method for measuring hormone levels in the laboratory.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The laboratory test for androsterone levels is indicated for the following conditions:

  • Cushing's Syndrome - This condition is characterized by excessive cortisol production, and elevated androsterone levels may be observed in affected patients.

2. Procedure

The procedure for testing androsterone levels involves several key steps to ensure accurate measurement of the hormone in the patient's blood.

  • Step 1: Patient Preparation - Prior to the test, it is crucial for the patient to refrain from taking any medications that may interfere with the results. Specifically, the patient should avoid adrenocorticotropic hormone (ACTH), steroids, and gonadotropins for at least 48 hours before the blood sample is collected. This preparation helps to ensure that the androsterone levels measured are reflective of the patient's natural hormone production.
  • Step 2: Venipuncture - A trained healthcare professional will perform a venipuncture, which involves inserting a needle into a vein to draw blood. This step is essential for obtaining the serum or plasma needed for the test. The venipuncture is a separately reportable procedure, and care must be taken to minimize discomfort and ensure the safety of the patient during the blood draw.
  • Step 3: Sample Processing - Once the blood sample is collected, it is processed to separate the serum or plasma from the cellular components of the blood. This separation is critical for accurate testing, as the hormone levels are measured in the liquid portion of the blood.
  • Step 4: Laboratory Analysis - The serum or plasma is then subjected to analysis using radioimmunoassay, a highly sensitive laboratory technique that allows for the precise measurement of hormone levels. This method utilizes radioactively labeled antibodies to detect the presence of androsterone in the sample.

3. Post-Procedure

After the procedure, patients may experience minor discomfort or bruising at the venipuncture site, which typically resolves quickly. There are no specific post-procedure care instructions required for this test, but patients should be advised to monitor the site for any unusual symptoms, such as excessive swelling or pain. The results of the androsterone test will be analyzed and reported by the laboratory, and the healthcare provider will discuss the findings with the patient during a follow-up appointment.

Short Descr ASSAY OF ANDROSTERONE
Medium Descr ANDROSTERONE
Long Descr Androsterone
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GA Waiver of liability statement issued as required by payer policy, individual case
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Date
Action
Notes
Pre-1990 Added Code added.
Code
Description
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