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Official Description

Nickel

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83885 refers to a laboratory test specifically designed to measure the levels of nickel in the body, which can be conducted using either blood or urine samples. Nickel is a heavy metal that, while essential in trace amounts for certain biological functions, can become toxic when present in excessive quantities. This toxicity is a significant concern as nickel can enter the human body through various environmental sources, including contaminated food, water, and air. The testing process involves obtaining a blood sample through a procedure known as venipuncture, which is a separate and reportable action. Alternatively, urine samples can be collected either as a random voided sample or as a 24-hour specimen, depending on the testing requirements. The analysis of both serum and urine samples is performed using a sophisticated technique called quantitative inductively coupled plasma-mass spectrometry (ICP-MS), which allows for precise measurement of nickel concentrations. This test is crucial for diagnosing potential nickel exposure and toxicity, guiding further medical evaluation and management.

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