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Official Description

Progesterone

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84144 refers to a laboratory test that measures the levels of progesterone in the blood. Progesterone is a steroid hormone that plays a crucial role in the reproductive system, particularly in the menstrual cycle and pregnancy. It is classified as a progestogen and is primarily produced by the corpus luteum, which forms in the ovary after ovulation. This hormone is essential for preparing the uterine lining for potential implantation of a fertilized egg and maintaining pregnancy. Additionally, progesterone is produced by the placenta during pregnancy and is also synthesized by the adrenal glands. The measurement of progesterone levels is significant for confirming ovulation, as elevated levels indicate that ovulation has occurred. Furthermore, assessing progesterone levels can provide insights into the function of the corpus luteum, which is vital for sustaining early pregnancy. The test is performed by obtaining a blood sample through venipuncture, which is a separate reportable procedure. The serum obtained from the blood sample is then analyzed using a chemiluminescent immunoassay, a sensitive and specific method for detecting hormone levels in the bloodstream.

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