© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 82274 refers to a laboratory test designed to detect the presence of occult blood in fecal samples through a qualitative immunoassay method. This test specifically targets human hemoglobin, utilizing goat antibodies to facilitate an antigen-antibody reaction that isolates the hemoglobin from the fecal matter. The immunoassay method is notable for its enhanced accuracy, as it significantly reduces the likelihood of false positive and false negative results that can arise from dietary influences and non-hemorrhagic components present in feces. This increased specificity is particularly beneficial for the detection of lower gastrointestinal bleeding, which can be indicative of serious conditions such as colon cancer or inflammatory bowel disease. The test allows for 1-3 simultaneous determinations, providing a comprehensive assessment of the patient's fecal samples for occult blood, thereby aiding in both diagnosis and monitoring of gastrointestinal health issues.
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