Need help choosing the right code?
Ask CasePilot about procedures, modifiers, bundling, and coding guidance.
Try CasePilot© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 84275 refers to a laboratory test that measures the levels of sialic acid in the blood. Sialic acid, scientifically known as N-Acetylneuraminic acid, is a derivative of neuraminic acid, which is a type of monosaccharide. This compound plays a significant role in various biological processes, particularly in the metabolism of certain proteins and fats. The measurement of sialic acid levels is particularly important in diagnosing and monitoring sialic acid storage diseases, which are genetic disorders caused by an autosomal recessive mutation. In these conditions, the body is unable to properly metabolize sialic acid, leading to elevated levels in the bloodstream. To perform this test, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. The serum obtained from the blood sample is then analyzed for lipid-associated sialic acid using a method called quantitative spectrophotometry, which allows for precise measurement of the sialic acid concentration in the serum.
© Copyright 2026 Coding Ahead. All rights reserved.
The sialic acid test (CPT® Code 84275) is indicated for the evaluation of patients who may have sialic acid storage diseases. These conditions are typically associated with specific genetic mutations that affect the metabolism of sialic acid. Elevated levels of sialic acid in the blood can suggest the presence of these disorders, making this test a valuable tool in the diagnostic process.
The procedure for measuring sialic acid levels involves several key steps. First, a healthcare professional will perform venipuncture, which is the process of puncturing a vein to obtain a blood sample. This step is crucial as it allows for the collection of serum, which is necessary for the subsequent analysis. Once the blood sample is collected, it is processed to separate the serum from the cellular components. The serum is then subjected to quantitative spectrophotometry, a laboratory technique that measures the concentration of sialic acid in the serum. This method involves passing light through the serum sample and measuring the amount of light absorbed, which correlates with the concentration of sialic acid present. The results of this test will provide valuable information regarding the patient's metabolic status and potential underlying conditions.
After the sialic acid test is completed, the patient may experience minimal discomfort at the venipuncture site, which typically resolves quickly. There are no specific post-procedure care instructions required for this test, but patients should be advised to monitor the site for any unusual symptoms, such as excessive bleeding or signs of infection. The results of the test will be interpreted by the healthcare provider, who will discuss the findings with the patient and determine any necessary follow-up actions based on the results.
| Short Descr | ASSAY OF SIALIC ACID | Medium Descr | ASSAY OF SIALIC ACID | Long Descr | Sialic acid | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
|
Date
|
Action
|
Notes
|
|---|---|---|
| 2013-01-01 | Changed | Medium Descriptor changed. |
| Pre-1990 | Added | Code added. |
Get instant expert-level medical coding assistance.