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Official Description

Riboflavin (Vitamin B-2)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84252 refers to a laboratory test that measures the levels of riboflavin, also known as Vitamin B2, in the blood. Riboflavin is an essential micronutrient that plays a critical role in various bodily functions, including growth and the production of red blood cells (RBCs). It is vital for the metabolism of macronutrients such as fats, proteins, and carbohydrates, as well as ketone bodies, which are produced during fat metabolism. Adequate daily intake of riboflavin is necessary to maintain optimal health, and deficiencies in this vitamin can lead to health issues, including anemia. The test involves obtaining a blood sample through a procedure known as venipuncture, which is reported separately. The plasma obtained from the blood sample is then analyzed using a technique called quantitative high-performance liquid chromatography (HPLC), which allows for precise measurement of riboflavin levels in the plasma. This test is important for diagnosing riboflavin deficiency and monitoring the nutritional status of patients.

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