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CPT®
82757

CPT® Code 82757

Official Description

Fructose, semen

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82757 refers to the laboratory test for measuring fructose levels in semen. Fructose is a type of sugar that is produced in the seminal vesicles and is essential for providing energy to sperm. This test is particularly important in the evaluation of male fertility, as the presence of fructose in seminal fluid is indicative of normal function of the seminal vesicles. When fructose levels are absent or significantly low, it may suggest potential issues such as obstruction in the seminal vesicles or the ejaculatory duct, or it may indicate a congenital absence of the vas deferens, which can affect fertility. The semen sample required for this test can be obtained through ejaculation or through other procedures that may need to be reported separately. The analysis of fructose levels in the semen is typically performed using quantitative spectrophotometry, a method that allows for precise measurement of the fructose concentration in the sample.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The fructose measurement in semen is indicated for the following conditions:

  • Infertility Evaluation This test is performed as part of the assessment of male infertility to determine the functionality of the seminal vesicles.
  • Assessment of Seminal Fluid Quality The presence or absence of fructose can help evaluate the quality of seminal fluid, which is crucial for sperm motility and overall fertility.
  • Investigation of Obstructive Conditions Low or absent fructose levels may indicate potential obstructions in the seminal vesicles or ejaculatory duct, warranting further investigation.
  • Congenital Anomalies The test may also be indicated in cases where congenital absence of the vas deferens is suspected, as this condition would affect fructose production.

2. Procedure

The procedure for testing fructose levels in semen involves several key steps:

  • Sample Collection A semen sample is collected, typically through ejaculation. In some cases, alternative methods may be employed to obtain the sample, which should be reported separately if applicable.
  • Sample Preparation Once collected, the semen sample is prepared for analysis. This may involve centrifugation or other techniques to separate the seminal fluid from sperm cells and other components.
  • Quantitative Spectrophotometry The fructose concentration in the prepared semen sample is measured using quantitative spectrophotometry. This method allows for accurate quantification of fructose levels, providing essential data for the evaluation of male reproductive health.

3. Post-Procedure

After the fructose measurement procedure, there are generally no specific post-procedure care requirements for the patient. However, it is important for the healthcare provider to discuss the results with the patient, as the interpretation of fructose levels can have significant implications for fertility assessments and potential further diagnostic evaluations. Patients may be advised to follow up with their healthcare provider to discuss the findings and any necessary next steps based on the results of the test.
Short Descr ASSAY OF SEMEN FRUCTOSE
Medium Descr ASSAY OF FRUCTOSE SEMEN
Long Descr Fructose, semen
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
Pre-1990 Added Code added.
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