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Official Description

Citrate

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82507 refers to a laboratory test that measures the levels of citrate, which is also known as citric acid, in either blood or urine samples. Citrate is a key component in the metabolic processes of the body, playing a significant role in energy production and the citric acid cycle, which is essential for cellular respiration. The measurement of citrate levels is particularly important in the context of nephrolithiasis, a condition characterized by the formation of kidney stones. Elevated or decreased citrate levels can provide valuable insights into the underlying metabolic conditions that may contribute to stone formation. For the test, a blood sample is typically obtained through a procedure known as venipuncture, which is a separate and reportable service. In addition to blood testing, urine samples can be collected either over a 24-hour period or as a single random sample, depending on the clinical requirements. The analysis of serum citrate levels is performed using spectrophotometry or enzymatic methodologies, which are standard laboratory techniques for quantifying biochemical substances. Urine citrate levels are assessed using quantitative enzymatic methodology, ensuring accurate measurement of citrate concentration in the urine. This comprehensive approach to testing allows healthcare providers to evaluate metabolic function and diagnose potential disorders related to citrate metabolism.

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