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The CPT® Code 82759 refers to a laboratory test that measures the levels of galactokinase in red blood cells (RBC). Galactokinase is an enzyme that plays a crucial role in the metabolism of galactose, a simple sugar found in various foods. This enzyme is part of the galactokinase, homoserine kinase, and mevalonate kinase (GHMP) family, which are essential for the biosynthesis of isoprenes and amino acids, as well as the metabolism of carbohydrates. When galactokinase is deficient, it can lead to a metabolic disorder known as galactosemia type 2, which typically presents in infancy and may result in serious complications such as infantile cataracts. The underlying cause of this deficiency is a mutation in the GAL12 gene, which is inherited in an autosomal recessive manner. To perform this test, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. The analysis of the whole blood or red blood cells is conducted using a quantitative radioisotopic methodology, ensuring accurate measurement of galactokinase levels in the sample.
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The galactokinase, RBC test (CPT® Code 82759) is indicated for the evaluation of patients who may have a deficiency of galactokinase, which can lead to galactosemia type 2. This condition is particularly relevant in infants who present with symptoms that may include:
The procedure for conducting the galactokinase, RBC test involves several key steps to ensure accurate results. First, a qualified healthcare professional performs a venipuncture to obtain a blood sample from the patient. This step is critical as it allows for the collection of whole blood or red blood cells necessary for the analysis. The blood sample is then processed in a laboratory setting where it undergoes quantitative radioisotopic methodology. This specific methodology is employed to measure the levels of galactokinase in the red blood cells accurately. The use of radioisotopes in the testing process enhances the sensitivity and specificity of the measurement, ensuring that even low levels of the enzyme can be detected. After the analysis is complete, the results are compiled and reported to the healthcare provider for further evaluation and management of the patient's condition.
After the galactokinase, RBC test is performed, there are generally no specific post-procedure care requirements for the patient. However, it is essential for the healthcare provider to monitor the patient for any potential adverse reactions to the venipuncture, such as bruising or discomfort at the site of blood collection. The results of the test will typically be reviewed in conjunction with the patient's clinical history and any presenting symptoms. If a deficiency is identified, further management and treatment options will be discussed with the patient and their family, particularly in cases where galactosemia type 2 is diagnosed.
| Short Descr | ASSAY OF RBC GALACTOKINASE | Medium Descr | ASSAY OF GALACTOKINASE RBC | Long Descr | Galactokinase, RBC | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. |
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| 2013-01-01 | Changed | Medium Descriptor changed. |
| Pre-1990 | Added | Code added. |
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