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The CPT® Code 83864 refers to a quantitative test for acid mucopolysaccharides, which are also known as glycosaminoglycans (GAGs). These are long-chain sugar molecules that play a crucial role in the structure and function of various tissues in the body, including bone, connective tissue, and joint fluid. The test is primarily conducted on a urine sample to assess the levels of these mucopolysaccharides. Conditions such as mucopolysaccharidosis (MPS) arise from genetically inherited metabolic syndromes, including Hunter syndrome, Hurler syndrome, Sanfilippo syndrome, Scheie syndrome, and Morquio syndrome. These syndromes are characterized by a deficiency of specific enzymes that are responsible for breaking down the sugar molecule chains, leading to an accumulation of mucopolysaccharides in the body. The quantitative test indicated by CPT® Code 83864 is particularly important for monitoring patients who have already been diagnosed with MPS, as it helps in tracking the levels of GAGs over time. For optimal results, a urine specimen is typically collected as the first morning void, although a 24-hour urine specimen may also be utilized. The analysis of the urine sample is performed using spectrophotometry, a method that measures the intensity of light absorbed by the sample, providing a quantitative assessment of the acid mucopolysaccharide levels present.
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The acid mucopolysaccharide test, represented by CPT® Code 83864, is indicated for the following conditions:
The procedure for conducting the acid mucopolysaccharide test involves several key steps:
After the acid mucopolysaccharide test is completed, the patient may not require any specific post-procedure care, as the test is non-invasive and does not involve any significant risks. However, it is essential for healthcare providers to communicate the results to the patient and discuss any necessary follow-up actions based on the findings. If elevated levels of mucopolysaccharides are detected, further diagnostic evaluations or referrals to specialists may be warranted to manage any underlying conditions effectively. Regular monitoring may also be recommended for patients with known mucopolysaccharidosis to track disease progression and treatment efficacy.
| Short Descr | MUCOPOLYSACCHARIDES | Medium Descr | MUCOPOLYSACCHARIDES ACID QUANTITATIVE | Long Descr | Mucopolysaccharides, acid, quantitative | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. | Q4 | Service for ordering/referring physician qualifies as a service exemption |
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| 2015-01-01 | Changed | Code description changed. |
| Pre-1990 | Added | Code added. |
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