CPT® Code 82172

The CPT® Code 82172 refers to the measurement of apolipoproteins, which are essential proteins that play a critical role in lipid metabolism. These proteins are composed of a protein molecule that is encased in lipids, allowing them to circulate effectively through the lymphatic and vascular systems without undergoing alteration. Specifically, Apolipoprotein-A is associated with high-density lipoproteins (HDL), while Apolipoprotein-B is linked to low-density lipoproteins (LDL). Both types of apolipoproteins are synthesized primarily in the liver and intestines. The measurement of these apolipoproteins is significant as it provides insight into an individual's risk for coronary artery disease (CAD) when expressed as a ratio. To obtain the necessary samples for testing, a fasting blood sample is collected through a procedure known as venipuncture, which is separately reportable. The analysis of the apolipoproteins is conducted using a method called quantitative nephelometry, which allows for precise measurement. If both Apolipoprotein-A and Apolipoprotein-B values are obtained, the code 82172 should be reported for the qualitative analysis of each apolipoprotein.