Need help choosing the right code?
Ask CasePilot about procedures, modifiers, bundling, and coding guidance.
Try CasePilot© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 83727 refers to the measurement of luteinizing releasing factor (LRF), which is also known as luteinizing releasing hormone (LRH). This hormone is synthesized in the hypothalamus and plays a crucial role in the regulation of the reproductive system by stimulating the pituitary gland to secrete two key hormones: follicle stimulating hormone (FSH) and luteinizing hormone (LH). The testing of LRF levels is particularly significant in the assessment of various reproductive health issues. It is commonly utilized to evaluate conditions such as delayed puberty in males, menstrual disorders in females, fertility challenges, and symptoms of hirsutism and virilization in women. The procedure typically involves administering gonadotropin releasing hormone, followed by the collection of multiple blood samples at 15-minute intervals over a duration of 1 to 2 hours. This method allows healthcare providers to assess the responsiveness of the pituitary gland to the administered hormone, providing valuable insights into the patient's hormonal function and reproductive health.
© Copyright 2026 Coding Ahead. All rights reserved.
The measurement of luteinizing releasing factor (LRF) is indicated for several specific conditions and symptoms that relate to reproductive health. These indications include:
The procedure for measuring luteinizing releasing factor (LRF) involves several key steps to ensure accurate assessment of the hormone levels. The process begins with the administration of gonadotropin releasing hormone (GnRH) to the patient. Following this injection, multiple blood samples are collected at 15-minute intervals. This sampling continues for a total duration of 1 to 2 hours. The timing of these samples is critical, as it allows for the evaluation of the pituitary gland's response to the administered GnRH. By analyzing the levels of LRF in the collected blood samples, healthcare providers can determine whether the pituitary gland is functioning normally and producing the appropriate levels of FSH and LH in response to the stimulation from GnRH.
After the procedure, patients may be monitored for any immediate reactions to the hormone injection. It is important to provide patients with information regarding potential side effects, although these are typically minimal. The results of the LRF testing will be analyzed and discussed with the patient in a follow-up appointment, where further steps or treatments may be recommended based on the findings. Patients should be advised to report any unusual symptoms or concerns following the procedure, and they may be instructed to resume normal activities unless otherwise directed by their healthcare provider.
| Short Descr | ASSAY OF LRH HORMONE | Medium Descr | LUTEINIZING RELEASING FACTOR | Long Descr | Luteinizing releasing factor (LRH) | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. |
|
Date
|
Action
|
Notes
|
|---|---|---|
| 2015-01-01 | Note | AMA Guidelines changed. |
| Pre-1990 | Added | Code added. |
Get instant expert-level medical coding assistance.