CPT® Code 82965

The CPT® Code 82965 refers to a laboratory test specifically designed to measure the level of glutamate dehydrogenase (GLDH) in the blood. GLDH is an important mitochondrial enzyme that plays a crucial role in the metabolism of carbon and nitrogen, particularly in the urea cycle. This test is often utilized as a differential diagnostic tool, especially when other liver function tests yield abnormal results. Elevated levels of GLDH can indicate hepatocytic necrosis, which may occur due to toxic substances or hypoxic conditions affecting the liver. It is important to note that GLDH levels do not rise in cases of inflammatory hepatitis, making this test particularly useful in distinguishing between different types of liver damage. The procedure involves obtaining a blood sample through venipuncture, which is a separately reportable service. The serum obtained from the blood sample is then analyzed using spectrophotometry, a method that measures the intensity of light absorbed by the serum, allowing for accurate quantification of GLDH levels.