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CPT®
82943

CPT® Code 82943

Official Description

Glucagon

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82943 refers to a laboratory test specifically designed to measure the level of glucagon, which is a crucial hormone produced by the pancreas. Glucagon plays a significant role in glucose metabolism by raising blood sugar levels; it does this by stimulating the liver to release glycogen stores through a process known as glycogenolysis. This test is particularly important in the clinical setting for evaluating and monitoring conditions such as glucagonoma, which is a type of tumor that produces excess glucagon, as well as other tumors that may also secrete glucagon. To perform this test, a blood sample is collected, typically through a procedure known as venipuncture, which is separately reportable. The plasma obtained from the blood sample is then analyzed using a qualitative radioimmunoassay, a sensitive technique that allows for the detection and quantification of glucagon levels in the plasma.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The glucagon level test (CPT® Code 82943) is indicated for specific clinical scenarios where monitoring or evaluation of glucagon levels is necessary. The following conditions may warrant the performance of this test:

  • Glucagonoma - This is a rare type of pancreatic tumor that secretes excessive amounts of glucagon, leading to hyperglycemia and other metabolic disturbances.
  • Other glucagon-producing tumors - Similar to glucagonoma, other neoplasms that produce glucagon may require monitoring through this test to assess their impact on blood glucose levels.

2. Procedure

The procedure for measuring glucagon levels involves several key steps that ensure accurate results. The following outlines the procedural steps involved:

  • Step 1: Patient Preparation - Prior to the test, the patient may be instructed to fast for a specific period to ensure that the glucagon levels are not influenced by recent food intake. This preparation is crucial for obtaining baseline measurements.
  • Step 2: Venipuncture - A qualified healthcare professional performs venipuncture to obtain a blood sample from the patient. This involves inserting a needle into a vein, typically in the arm, to draw blood into a collection tube. The venipuncture procedure is essential as it provides the plasma needed for testing.
  • Step 3: Plasma Separation - Once the blood sample is collected, it is processed to separate the plasma from the cellular components. This is typically done through centrifugation, which spins the blood at high speeds to separate the different components based on density.
  • Step 4: Qualitative Radioimmunoassay - The separated plasma is then subjected to a qualitative radioimmunoassay, a laboratory technique that uses radioactively labeled antibodies to detect and quantify the glucagon levels present in the plasma sample. This method is sensitive and allows for accurate measurement of glucagon concentrations.

3. Post-Procedure

After the glucagon level test is completed, there are generally no specific post-procedure care requirements for the patient. However, it is important to monitor the patient for any immediate reactions to the venipuncture, such as bleeding or discomfort at the site. The results of the glucagon test will be analyzed and reported, providing valuable information for the healthcare provider to evaluate the patient's condition, particularly in relation to glucagonoma or other glucagon-producing tumors. Follow-up appointments may be necessary to discuss the results and any further diagnostic or therapeutic steps that may be required based on the findings.
Short Descr ASSAY OF GLUCAGON
Medium Descr ASSAY OF GLUCAGON
Long Descr Glucagon
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
Pre-1990 Added Code added.
Code
Description
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