CPT® Code 84134

The CPT® Code 84134 refers to a laboratory test that measures the levels of prealbumin in the blood. Prealbumin, also known as transthyretin (TTR), is a protein that plays a crucial role in the transport of thyroxin, a hormone produced by the thyroid gland, and retinol binding protein, which carries vitamin A (retinol) in the bloodstream. This test is particularly significant in clinical settings as it helps assess nutritional status, especially in patients who are chronically or critically ill. The measurement of prealbumin levels can provide valuable insights into protein-calorie malnutrition, which is a common concern in these populations. The test is performed on a blood sample, which is typically obtained through a procedure known as venipuncture. This involves puncturing a vein to collect blood for analysis. The serum or plasma obtained from the blood sample is then tested using an immunoturbidimetric method, a laboratory technique that quantifies the concentration of proteins in the sample. Prealbumin levels can vary based on several factors. Elevated levels may occur due to the use of high-dose corticosteroids or non-steroidal anti-inflammatory drugs (NSAIDs), as well as in conditions such as adrenal gland disorders, Hodgkin's disease, and kidney failure. Conversely, decreased prealbumin levels can indicate various health issues, including hyperthyroidism, liver disease, severe infections, inflammatory diseases, and certain digestive disorders. Understanding these levels is essential for healthcare providers in diagnosing and managing patients' nutritional and health status.