CPT® Code 84140

The CPT® Code 84140 refers to a laboratory test that measures the levels of pregnenolone in the blood. Pregnenolone is a steroid hormone that serves as a precursor to several other important hormones, including progesterone, androgens, estrogens, mineralocorticoids, and glucocorticoids. It is synthesized from cholesterol, which is a fundamental building block for steroid hormones. The measurement of pregnenolone levels can provide valuable insights into various hormonal functions and imbalances within the body. To perform this test, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. The analysis of the serum or plasma is conducted using a sophisticated technique called quantitative high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). This method allows for precise quantification of pregnenolone levels, aiding healthcare providers in diagnosing and managing conditions related to hormonal imbalances.