Need help choosing the right code?
Ask CasePilot about procedures, modifiers, bundling, and coding guidance.
Try CasePilot© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 84207 refers to a laboratory test that measures the levels of pyridoxal phosphate, which is the active form of Vitamin B6, in the blood. This test is crucial for assessing the nutritional status of Vitamin B6 in the body. Pyridoxal phosphate plays a vital role as a coenzyme in numerous biochemical reactions, including those involved in amino acid and lipid metabolism, gluconeogenesis, and the synthesis of neurotransmitters and histamine. Additionally, it is essential for hemoglobin synthesis and function, as well as gene expression. The measurement of pyridoxal 5-phosphate levels provides a reliable indicator of Vitamin B6 status, which is important for various physiological functions. To perform this test, a blood sample is collected through venipuncture, which is a procedure that can be reported separately. The serum or plasma obtained from the blood sample is then analyzed using quantitative high-performance liquid chromatography, a precise method that allows for accurate measurement of the vitamin levels in the body.
© Copyright 2026 Coding Ahead. All rights reserved.
The test for pyridoxal phosphate (Vitamin B-6) is indicated for various clinical scenarios where assessment of Vitamin B6 levels is necessary. The following conditions may warrant this test:
The procedure for measuring pyridoxal phosphate levels involves several key steps that ensure accurate results. First, a qualified healthcare professional performs venipuncture to obtain a blood sample from the patient. This step is critical as it allows for the collection of serum or plasma, which is necessary for the subsequent analysis. The blood sample is then processed to separate the serum or plasma from the cellular components. Once the serum or plasma is prepared, it is subjected to quantitative high-performance liquid chromatography (HPLC). This sophisticated analytical technique enables the precise measurement of pyridoxal 5-phosphate levels in the sample. The results obtained from this analysis provide valuable information regarding the patient's Vitamin B6 nutritional status, which can guide further clinical decisions and interventions.
After the blood sample has been collected and processed, there are generally no specific post-procedure care requirements for the patient. However, it is advisable for patients to remain hydrated and to follow any additional instructions provided by their healthcare provider. The results of the pyridoxal phosphate test will typically be available within a few days, and healthcare professionals will discuss the findings with the patient to determine if any further action or treatment is necessary based on the Vitamin B6 levels measured.
| Short Descr | ASSAY OF VITAMIN B-6 | Medium Descr | ASSAY OF PYRIDOXAL PHOSPHATE | Long Descr | Pyridoxal phosphate (Vitamin B-6) | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. | GZ | Item or service expected to be denied as not reasonable and necessary | GA | Waiver of liability statement issued as required by payer policy, individual case | Q4 | Service for ordering/referring physician qualifies as a service exemption | 59 | Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25. | 26 | Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number. | 76 | Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service. | 77 | Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service. | 91 | Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient. | GW | Service not related to the hospice patient's terminal condition | GY | Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit | Q1 | Routine clinical service provided in a clinical research study that is in an approved clinical research study | XE | Separate encounter, a service that is distinct because it occurred during a separate encounter | XS | Separate structure, a service that is distinct because it was performed on a separate organ/structure | XU | Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service |
|
Date
|
Action
|
Notes
|
|---|---|---|
| 2013-01-01 | Changed | Medium Descriptor changed. |
| Pre-1990 | Added | Code added. |
Get instant expert-level medical coding assistance.