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Official Description

Urea nitrogen, urine

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84540 refers to the laboratory test for measuring urea nitrogen in urine, specifically known as urine urea nitrogen. Urea nitrogen is a waste product formed in the liver during the metabolism of proteins, which undergoes a series of chemical reactions collectively known as the urea cycle or Krebs-Henseleit cycle. Once produced, urea enters the bloodstream and is subsequently filtered by the kidneys, where it is excreted in the urine. The measurement of blood urea nitrogen (BUN) levels is crucial for assessing renal function, as it provides insights into how well the kidneys are performing their filtering duties. This test is particularly important for monitoring patients with existing renal diseases and evaluating the effectiveness of dialysis treatments. Additionally, BUN levels may be analyzed in patients suffering from acute or chronic illnesses that could potentially impact kidney function. It is important to note that this specific code (84540) pertains solely to the measurement of BUN in urine, distinguishing it from related codes such as 84525, which involves a reagent strip test, and 84545, which requires a 24-hour urine collection for analysis.

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