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Official Description

Myeloperoxidase (MPO)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83876 refers to the measurement of myeloperoxidase (MPO) levels in a blood sample. Myeloperoxidase is an enzyme produced by white blood cells, specifically neutrophils, and serves as a biomarker for cardiovascular risk assessment. The procedure involves obtaining a blood sample through a venipuncture, which is a standard method for drawing blood. This test is particularly significant as it helps identify patients who may be at an increased risk for myocardial infarction, commonly known as a heart attack, and those who may require cardiac revascularization procedures, which are interventions aimed at restoring blood flow to the heart. The quantification of myeloperoxidase is typically performed using an enzyme-linked immunosorbent assay (ELISA), a laboratory technique that allows for the precise measurement of this biomarker in the blood plasma. Elevated levels of myeloperoxidase in patients presenting with chest pain can indicate a higher likelihood of experiencing major cardiac events, making this test a valuable tool in the early identification and management of cardiovascular conditions.

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