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The CPT® Code 82485 refers to a laboratory test that quantitatively measures chondroitin B sulfate, a specific type of glycosaminoglycan (GAG). Chondroitin B sulfate is a complex molecule composed of polysaccharides linked to amino acids, which are essential components of the extracellular matrix found in various tissues, including skin, cartilage, corneal tissue, and the umbilical cord. This matrix serves multiple functions, providing mechanical support to tissues while facilitating the diffusion of water-soluble molecules and the migration of cells. The presence of glycosaminoglycans, such as chondroitin B sulfate, is crucial for maintaining the homeostasis of connective tissues, influencing neurobiochemical activities, and playing roles in coagulation, cell growth, and tissue repair. Notably, elevated levels of chondroitin B sulfate in the body may be indicative of certain pathological conditions, particularly in relation to atherosclerosis, where they may correlate with the presence and characteristics of atherosclerotic plaques, distinguishing between hard and soft types.
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The laboratory test for chondroitin B sulfate is indicated for the assessment of various conditions related to connective tissue and cardiovascular health. Elevated levels of chondroitin B sulfate may suggest the presence of atherosclerotic plaque, which can be classified into different types based on their hardness. This test may be utilized in the evaluation of patients with suspected cardiovascular diseases or those exhibiting symptoms related to connective tissue disorders.
The procedure for measuring chondroitin B sulfate quantitatively involves several key steps to ensure accurate results. Initially, a blood sample is collected from the patient, typically through venipuncture. This sample is then processed in a laboratory setting where it undergoes specific analytical techniques designed to isolate and quantify the chondroitin B sulfate present in the serum. The laboratory may employ methods such as enzyme-linked immunosorbent assay (ELISA) or mass spectrometry, depending on the facility's capabilities and the required sensitivity of the test. After the analysis is complete, the results are compiled and interpreted by a qualified laboratory professional, who will report the findings to the requesting physician for further evaluation and clinical decision-making.
Post-procedure care for patients undergoing the chondroitin B sulfate test is generally minimal, as it is a routine laboratory test. Patients may experience slight discomfort or bruising at the venipuncture site, which typically resolves quickly. There are no specific restrictions or follow-up procedures required after the test, and patients can resume their normal activities immediately. The results of the test will be communicated to the healthcare provider, who will discuss the implications of the findings and any necessary further actions based on the patient's clinical context.
| Short Descr | ASSAY CHONDROITIN SULFATE | Medium Descr | CHONDROITIN B SULFATE QUANTITATIVE | Long Descr | Chondroitin B sulfate, quantitative | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
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| 2011-01-01 | Changed | Short description changed. |
| Pre-1990 | Added | Code added. |
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