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Official Description

Etiocholanolone

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82696 refers to a laboratory test specifically designed to measure the level of etiocholanolone, which is an inactive androgenic ketosteroid. This compound is metabolized from testosterone and androstenedione through the action of the enzyme 5-beta-reductase. Understanding the levels of etiocholanolone in the body is significant because elevated concentrations can lead to various physiological responses, including fever, immunostimulation, and leukocytosis, which is an increase in white blood cells. Additionally, etiocholanolone is known to exert anticonvulsant effects by interacting with GABA receptors, thereby influencing seizure susceptibility. This makes the measurement of etiocholanolone particularly relevant in certain clinical contexts. Notably, individuals suffering from androgenic alopecia, commonly referred to as male pattern baldness, frequently exhibit elevated levels of etiocholanolone in their urine. The test requires the collection of a blood sample, which is obtained through a separately reportable venipuncture, while urine can be collected either by random voided specimen or through catheterization, depending on the clinical requirements.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The etiocholanolone test (CPT® Code 82696) is indicated for the following conditions:

  • Elevated Etiocholanolone Levels Elevated levels of etiocholanolone may be associated with fever, immunostimulation, and leukocytosis.
  • Anticonvulsant Effects The measurement may be relevant for assessing anticonvulsant effects on GABA receptors and modulating seizure susceptibility.
  • Androgenic Alopecia Individuals with androgenic alopecia, or male pattern baldness, often present with increased levels of etiocholanolone in their urine.

2. Procedure

The procedure for measuring etiocholanolone involves several key steps that ensure accurate collection and analysis of the samples. First, a blood sample is obtained through venipuncture, which is a standard method for drawing blood from a vein. This step is crucial as it provides the necessary serum for testing. The venipuncture must be performed by a qualified healthcare professional to ensure the integrity of the sample. Following the blood collection, urine is collected for analysis. This can be done either by a random voided specimen, where the patient provides a sample at any time during the day, or through catheterization, which involves inserting a catheter into the bladder to obtain a more controlled urine sample. The choice of collection method may depend on the clinical scenario and the specific requirements of the test. Once both samples are collected, they are sent to the laboratory for analysis, where the levels of etiocholanolone will be measured using appropriate laboratory techniques.

3. Post-Procedure

After the procedure, there are generally no specific post-procedure care requirements for patients. However, it is important to monitor the patient for any immediate reactions to the venipuncture, such as bleeding or discomfort at the site. Patients may resume normal activities following the blood draw and urine collection. The results of the etiocholanolone test will typically be available within a specified timeframe, and healthcare providers will discuss the findings with the patient to determine any necessary follow-up actions or treatments based on the results.

Short Descr ASSAY OF ETIOCHOLANOLONE
Medium Descr ASSAY OF ETIOCHOLANOLONE
Long Descr Etiocholanolone
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
GA Waiver of liability statement issued as required by payer policy, individual case
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
Pre-1990 Added Code added.
Code
Description
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