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Official Description

Somatostatin

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84307 refers to a laboratory test specifically designed to measure the levels of somatostatin in the blood. Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF), is a crucial inhibitory hormone that plays a significant role in the regulation of the endocrine system. It is produced in various locations within the body, including the stomach, intestine, delta cells of the pancreas, and the brain. The primary function of somatostatin is to inhibit the release of several secondary hormones, which include thyroid-stimulating hormone, growth hormone, and various gastrointestinal hormones. This regulation is vital for maintaining hormonal balance and proper physiological function. To perform this test, a blood sample is collected through a procedure known as venipuncture, which is separately reportable. The plasma obtained from the blood sample is then analyzed using a quantitative extraction method combined with radioimmunoassay techniques, allowing for precise measurement of somatostatin levels in the bloodstream.

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