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Official Description

Sulfate, urine

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84392 refers to a laboratory test that measures the levels of sulfate in urine. This test is significant as it provides insights into an individual's dietary protein intake and overall nutritional status. Sulfate levels in urine are influenced by the consumption of protein, particularly from animal sources such as meat, fish, and poultry, which are rich in sulfur-containing amino acids like methionine and cysteine. When an individual consumes a high amount of animal protein, it can lead to increased excretion of sulfur and calcium in the urine. This elevated excretion may raise the risk of developing renal calculi, commonly known as kidney stones. Additionally, urine sulfates play a crucial role in the body's buffering system and in the exchange of hydrogen ions, which helps to regulate the supersaturation of uric acid in the urine. The test typically involves collecting urine over a 24-hour period, followed by analysis using quantitative spectrophotometry to accurately measure sulfate concentrations.

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