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CPT®
83582

CPT® Code 83582

Official Description

Ketogenic steroids, fractionation

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83582 refers to a laboratory test specifically designed to measure fractionated ketogenic steroids. Ketogenic steroids are a category of corticosteroids that possess a hydroxyl group and a short carbon chain on their steroid nucleus. This group includes important adrenal hormones such as cortisol, cortisone, 11-desoxycortisol, and deoxycorticosterone, along with their tetrahydroderivatives. The measurement of these steroids is crucial in diagnosing and managing various endocrine disorders. Elevated levels of ketogenic steroids can indicate conditions such as adrenal hyperplasia, which may lead to precocious puberty, Cushing syndrome, obesity, and other pathological stress situations, including acute illness, infections, surgical interventions, and severe burns. Conversely, decreased levels of these steroids may suggest adrenal insufficiencies, such as Addison's disease, adrenocorticotropic hormone (ACTH) deficiency, or hypopituitarism. Understanding the levels of ketogenic steroids is essential for healthcare professionals in evaluating adrenal function and diagnosing related disorders.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 83582 is indicated for the evaluation of various medical conditions that may affect adrenal hormone production and metabolism. The following conditions may warrant the performance of this laboratory test:

  • Adrenal Hyperplasia This condition can lead to an overproduction of adrenal hormones, including ketogenic steroids, which may result in precocious puberty.
  • Cushing Syndrome Characterized by excessive cortisol production, this syndrome can cause elevated levels of ketogenic steroids.
  • Obesity Increased body weight may be associated with altered steroid metabolism, leading to elevated ketogenic steroid levels.
  • Pathological Stress Conditions Situations such as acute illness, infections, surgical procedures, and severe burns can trigger an increase in ketogenic steroid levels due to the body's stress response.
  • Addison's Disease This condition is characterized by insufficient production of adrenal hormones, which may result in decreased levels of ketogenic steroids.
  • ACTH Deficiency A lack of adrenocorticotropic hormone can lead to reduced adrenal steroid production, including ketogenic steroids.
  • Hypopituitarism This disorder can affect the pituitary gland's ability to produce hormones that stimulate adrenal function, potentially resulting in decreased ketogenic steroid levels.

2. Procedure

The procedure for measuring fractionated ketogenic steroids involves several key steps to ensure accurate results. The following outlines the procedural steps:

  • Step 1: Sample Collection A blood sample is collected from the patient, typically through venipuncture. Proper collection techniques are essential to avoid contamination and ensure the integrity of the sample.
  • Step 2: Sample Preparation The collected blood sample is processed in the laboratory. This may involve centrifugation to separate the serum or plasma from the cellular components of the blood, which is necessary for accurate measurement of the steroid levels.
  • Step 3: Analytical Testing The prepared sample undergoes analytical testing using specific laboratory techniques, such as chromatography or mass spectrometry, to quantify the levels of various ketogenic steroids present in the sample.
  • Step 4: Data Interpretation Once the analysis is complete, the results are interpreted by qualified laboratory personnel. They will compare the measured levels of ketogenic steroids against established reference ranges to determine if the levels are elevated or decreased.
  • Step 5: Reporting Results The final results are compiled into a report, which is then sent to the requesting healthcare provider. This report will include the measured levels of each steroid, any relevant notes on the testing process, and interpretations based on the findings.

3. Post-Procedure

After the procedure, there are generally no specific post-procedure care requirements for the patient, as the test is minimally invasive. Patients may resume normal activities immediately following the blood draw. However, it is important for healthcare providers to discuss the results with the patient once they are available. The interpretation of the ketogenic steroid levels can provide valuable insights into the patient's adrenal function and overall health status. Follow-up testing or additional evaluations may be necessary based on the results obtained from the ketogenic steroid measurement.
Short Descr ASSAY OF KETOGENIC STEROIDS
Medium Descr ASSAY OF KETOGENIC STEROIDS FRACTIONATION
Long Descr Ketogenic steroids, fractionation
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
Pre-1990 Added Code added.
Code
Description
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