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Official Description

Homocysteine

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83090 refers to a laboratory test specifically designed to measure the levels of homocysteine in the blood. Homocysteine is a sulfur-containing amino acid that is produced in the body as a result of the metabolism of methionine, an essential amino acid obtained from dietary protein. The measurement of homocysteine levels is significant because elevated concentrations of this amino acid have been identified as a potential risk factor for cardiovascular diseases, including heart attacks and strokes. In addition to cardiovascular risks, high homocysteine levels can also be indicative of other health issues, such as vitamin B deficiencies, which are crucial for the proper metabolism of homocysteine. Other factors that may lead to increased homocysteine levels include intense or prolonged physical exercise, chronic alcoholism, and certain inherited genetic disorders that affect metabolism. The test is performed by obtaining a blood sample through venipuncture, which is a procedure that involves puncturing a vein to collect blood. The analysis of the blood sample is conducted using a quantitative enzymatic technique, which allows for precise measurement of homocysteine levels in either serum or plasma.

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