Coding Ahead
CasePilot
Medical Coding Assistant
Case2Code
Search and Code Lookup Tool
CareerCenter
Medical Coding Job Board
Log in Register free account

Need help choosing the right code?

Ask CasePilot about procedures, modifiers, bundling, and coding guidance.

Try CasePilot

Official Description

Protein, total, by refractometry, any source

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Total protein levels are an important indicator of a patient's overall nutritional status and can be measured in various bodily fluids, including urine, serum, cerebral spinal fluid, and synovial fluid. The measurement is performed using a technique known as refractometry, which assesses the concentration of proteins in the sample. This method involves obtaining a sample from the patient, which may include blood, urine, amniotic fluid, or serum. Once the sample is collected, the total protein level is determined, providing valuable information regarding the patient's health. Elevated or decreased protein levels can indicate various medical conditions, making this test a crucial component of patient assessment and management.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The total protein measurement by refractometry is indicated for various clinical scenarios, including:

  • Assessment of Nutritional Status This test helps evaluate the overall nutritional level of the patient, which is essential for diagnosing malnutrition or other dietary deficiencies.
  • Diagnosis of Disease Abnormal total protein levels can indicate the presence of diseases such as liver disease, kidney disease, or inflammatory conditions.
  • Monitoring of Disease Progression Regular measurement of total protein levels can assist in monitoring the progression of certain diseases and the effectiveness of treatment.

2. Procedure

The procedure for measuring total protein by refractometry involves several key steps:

  • Sample Collection A sample is obtained from the patient, which may include blood, urine, amniotic fluid, or serum. The choice of sample depends on the clinical context and the specific information needed.
  • Preparation of the Sample The collected sample may need to be processed or diluted according to laboratory protocols to ensure accurate measurement during the refractometry analysis.
  • Refractometry Measurement The prepared sample is then subjected to refractometry, where the refractive index of the sample is measured. This index correlates with the concentration of proteins present in the fluid.
  • Result Interpretation The results are analyzed and interpreted by healthcare professionals, providing insights into the patient's total protein levels and overall health status.

3. Post-Procedure

After the total protein measurement procedure, there are generally no specific post-procedure care requirements. However, healthcare providers may advise patients on the significance of the results and any necessary follow-up actions based on the findings. It is important for patients to discuss their results with their healthcare provider to understand the implications for their health and any further testing or treatment that may be required.

Short Descr ASSAY OF PROTEIN ANY SOURCE
Medium Descr PROTEIN TOTAL REFRACTOMETRY ANY SRC
Long Descr Protein, total, by refractometry, any source
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
Date
Action
Notes
2011-01-01 Changed Short description changed.
2004-01-01 Changed Code description changed.
Pre-1990 Added Code added.
Code
Description
Code
Description
CasePilot

Get instant expert-level medical coding assistance.

Ask about:
CPT Codes Guidelines Modifiers Crosswalks NCCI Edits Compliance Medicare Coverage
Example: "What is CPT code 99213?" or "Guidelines for E/M services"