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The CPT® Code 84210 refers to a laboratory test that measures the levels of pyruvate, also known as pyruvic acid, in blood and cerebrospinal fluid (CSF). Pyruvate is a crucial alpha-keto acid that plays a significant role in cellular energy production, particularly during the citric acid cycle, which is essential for aerobic and anaerobic metabolism. This test is particularly important in the context of diagnosing mitochondrial metabolic disorders, as it helps to assess the metabolic state of the body. The procedure involves the simultaneous collection of blood and CSF samples, which are then analyzed to determine the concentration of pyruvate. The blood sample is obtained through a procedure known as venipuncture, which is reported separately, while the CSF is collected via a lumbar puncture, commonly referred to as a spinal tap, which is also reported separately. The analysis of both whole blood and CSF is conducted using a quantitative enzymatic method, ensuring accurate measurement of pyruvate levels for diagnostic purposes.
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The pyruvate test (CPT® Code 84210) is indicated for the evaluation of various metabolic conditions, particularly those related to mitochondrial function. The following conditions may warrant this test:
The procedure for obtaining and testing pyruvate levels involves several key steps, which are detailed below:
After the collection of blood and CSF samples, patients may experience some minor discomfort or side effects, particularly from the lumbar puncture, which can include headache or soreness at the puncture site. It is important for healthcare providers to monitor patients for any adverse reactions following the procedures. The results of the pyruvate test will typically be available within a specified timeframe, allowing for timely diagnosis and management of any identified metabolic disorders. Follow-up consultations may be necessary to discuss the results and any further diagnostic or therapeutic steps that may be required based on the findings.
| Short Descr | ASSAY OF PYRUVATE | Medium Descr | ASSAY OF PYRUVATE | Long Descr | Pyruvate | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. |
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| 2013-01-01 | Changed | Medium Descriptor changed. |
| Pre-1990 | Added | Code added. |
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