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Official Description

Pyruvate

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 84210 refers to a laboratory test that measures the levels of pyruvate, also known as pyruvic acid, in blood and cerebrospinal fluid (CSF). Pyruvate is a crucial alpha-keto acid that plays a significant role in cellular energy production, particularly during the citric acid cycle, which is essential for aerobic and anaerobic metabolism. This test is particularly important in the context of diagnosing mitochondrial metabolic disorders, as it helps to assess the metabolic state of the body. The procedure involves the simultaneous collection of blood and CSF samples, which are then analyzed to determine the concentration of pyruvate. The blood sample is obtained through a procedure known as venipuncture, which is reported separately, while the CSF is collected via a lumbar puncture, commonly referred to as a spinal tap, which is also reported separately. The analysis of both whole blood and CSF is conducted using a quantitative enzymatic method, ensuring accurate measurement of pyruvate levels for diagnostic purposes.

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