© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 82728 refers to the laboratory test for measuring ferritin levels in the blood. Ferritin is a crucial intracellular protein that plays a significant role in iron metabolism by storing iron and regulating its release into the bloodstream. This controlled release is essential for maintaining the body's iron balance, preventing both iron overload and deficiency. The measurement of ferritin levels is particularly important in clinical settings for diagnosing and monitoring various conditions. Elevated ferritin levels may indicate excess iron storage, which can occur in diseases such as hemochromatosis or as a consequence of multiple blood transfusions. Conversely, decreased ferritin levels are indicative of iron deficiency, which can lead to anemia and other health issues. The test is performed by obtaining a blood sample through venipuncture, which is a separate reportable procedure. The serum obtained from the blood sample is then analyzed using a quantitative chemiluminescent immunoassay, a sensitive and specific method for determining ferritin concentration in the serum.
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