CPT® Code 84430

The CPT® Code 84430 refers to the laboratory test for measuring thiocyanate levels in blood or urine. Thiocyanate, also known as rhodanide, plays a crucial role in the human host defense system. It is produced during the metabolism of the amino acid cysteine and is involved in the detoxification process of cyanide, a potentially harmful substance. The measurement of thiocyanate levels is significant as elevated levels can indicate exposure to certain environmental factors, such as tobacco use or inhalation of environmental smoke. Additionally, patients receiving the medication nitroprusside may also exhibit increased thiocyanate levels. Conversely, decreased levels of thiocyanate can be observed in individuals suffering from specific diseases, such as cystic fibrosis. The test requires a blood sample, which is obtained through a separately reportable venipuncture procedure, or a urine sample, which can be collected either as a random void or through a 24-hour specimen collection. The analysis of serum, plasma, and urine samples is conducted using quantitative colorimetry, a method that allows for precise measurement of thiocyanate concentrations.