Need help choosing the right code?
Ask CasePilot about procedures, modifiers, bundling, and coding guidance.
Try CasePilot© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 82963 refers to a laboratory test that measures the level of beta-glucosidase, which is an enzyme essential for the metabolism of carbohydrates. This enzyme plays a critical role in breaking down complex carbohydrates into simpler sugars that the body can utilize. A deficiency or absence of beta-glucosidase is notably associated with Gaucher's disease, a type of lysosomal storage disorder characterized by the accumulation of certain fatty substances in the body due to the enzyme's inability to function properly. Additionally, low levels of this enzyme may also indicate ischemic liver injury, a condition where the liver is damaged due to a lack of blood flow. When the results of the beta-glucosidase test are abnormal, it is recommended that further genetic studies be conducted to explore the underlying causes. The test is performed on a blood sample, which is obtained through a procedure known as venipuncture, and the analysis of leukocytes is carried out using a technique called fluorometry, allowing for precise measurement of the enzyme levels in the sample.
© Copyright 2026 Coding Ahead. All rights reserved.
The beta-glucosidase test (CPT® Code 82963) is indicated for the evaluation of conditions associated with enzyme deficiencies. The primary indications for performing this test include:
The procedure for conducting the beta-glucosidase test involves several key steps, which are outlined as follows:
After the beta-glucosidase test is completed, the patient may experience minimal discomfort at the venipuncture site, which typically resolves quickly. There are no specific post-procedure care instructions required for the patient, but they should be advised to monitor the site for any unusual swelling or bleeding. If the test results indicate abnormal levels of beta-glucosidase, further genetic studies may be recommended to investigate potential underlying conditions. It is important for healthcare providers to discuss the results with the patient and outline any necessary follow-up actions based on the findings.
| Short Descr | ASSAY OF GLUCOSIDASE | Medium Descr | ASSAY OF GLUCOSIDASE BETA | Long Descr | Glucosidase, beta | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 233 - Laboratory - Chemistry and Hematology |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. |
|
Date
|
Action
|
Notes
|
|---|---|---|
| 2013-01-01 | Changed | Medium Descriptor changed. |
| Pre-1990 | Added | Code added. |
Get instant expert-level medical coding assistance.