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Official Description

Glucosidase, beta

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 82963 refers to a laboratory test that measures the level of beta-glucosidase, which is an enzyme essential for the metabolism of carbohydrates. This enzyme plays a critical role in breaking down complex carbohydrates into simpler sugars that the body can utilize. A deficiency or absence of beta-glucosidase is notably associated with Gaucher's disease, a type of lysosomal storage disorder characterized by the accumulation of certain fatty substances in the body due to the enzyme's inability to function properly. Additionally, low levels of this enzyme may also indicate ischemic liver injury, a condition where the liver is damaged due to a lack of blood flow. When the results of the beta-glucosidase test are abnormal, it is recommended that further genetic studies be conducted to explore the underlying causes. The test is performed on a blood sample, which is obtained through a procedure known as venipuncture, and the analysis of leukocytes is carried out using a technique called fluorometry, allowing for precise measurement of the enzyme levels in the sample.

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