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Official Description

Anti-mullerian hormone (AMH)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The Anti-Mullerian Hormone (AMH) test, identified by CPT® Code 82166, is a laboratory procedure that quantifies the concentration of AMH in the bloodstream. This hormone is produced by the ovarian follicles, which are the fluid-filled sacs that contain and release eggs. The measurement of AMH levels is particularly significant in the context of reproductive health, as it provides insights into a woman's ovarian reserve, which refers to the number of viable eggs remaining in the ovaries. While AMH levels can indicate the quantity of eggs, it is important to note that they do not serve as a direct predictor of fertility. As women age, AMH levels typically decline, with higher concentrations observed in younger women, particularly around the age of 25, compared to those in their mid to late 30s and beyond. This decline in AMH is a natural part of the aging process and can influence a woman's reproductive timeline. Clinicians often utilize AMH testing to assist in planning infertility treatments, as the results can inform decisions regarding the use of injectable fertility medications and the stimulation of the ovaries to enhance egg production. Additionally, AMH levels have diagnostic implications beyond fertility. They can be instrumental in identifying certain ovarian conditions, such as granulosa cell tumors, and in monitoring the effectiveness of treatment for these tumors. Furthermore, elevated AMH levels may be associated with polycystic ovarian syndrome (PCOS), a common endocrine disorder that can affect a woman's menstrual cycle and fertility. Overall, the AMH test is a valuable tool in both fertility assessment and the management of specific ovarian health issues.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The Anti-Mullerian Hormone (AMH) test is indicated for several specific clinical scenarios related to reproductive health and ovarian function. The following conditions and situations warrant the use of this test:

  • Infertility Assessment - The AMH test is commonly performed to evaluate a woman's ovarian reserve, which is crucial in planning infertility treatments.
  • Monitoring Fertility Treatments - AMH levels can help determine the effectiveness of injectable fertility medications and assess whether the ovaries are being adequately stimulated to produce more eggs.
  • Diagnosis of Ovarian Masses - The test may be utilized to diagnose if an ovarian mass is of the granulosa cell type, which is a specific type of tumor that can affect ovarian function.
  • Monitoring Treatment Efficacy - AMH levels can be monitored to evaluate the effectiveness of treatment for ovarian tumors and to check for recurrence of these tumors.
  • Polycystic Ovarian Syndrome (PCOS) - Elevated AMH levels may indicate the presence of PCOS, a condition that can lead to various reproductive and metabolic issues.

2. Procedure

The procedure for obtaining the Anti-Mullerian Hormone (AMH) test involves several key steps that ensure accurate measurement of the hormone levels in the blood. The following outlines the procedural steps:

  • Step 1: Patient Preparation - Prior to the test, patients may be advised to avoid certain medications or supplements that could affect hormone levels. It is essential for patients to follow any specific instructions provided by their healthcare provider to ensure the accuracy of the test results.
  • Step 2: Blood Sample Collection - A healthcare professional will perform a venipuncture to draw a blood sample, typically from a vein in the arm. This process is performed using standard sterile techniques to minimize the risk of infection.
  • Step 3: Sample Handling - Once the blood sample is collected, it is processed in a laboratory setting. The serum is separated from the blood cells and prepared for analysis to measure the AMH concentration.
  • Step 4: Laboratory Analysis - The laboratory utilizes specific assays to quantify the AMH levels in the serum. These assays are designed to provide precise measurements, which are crucial for interpreting the results accurately.
  • Step 5: Result Interpretation - After the analysis is complete, the results are compiled and interpreted by a qualified healthcare professional. The AMH levels are then discussed with the patient, providing insights into their ovarian reserve and potential implications for fertility.

3. Post-Procedure

After the AMH test is completed, there are generally no specific post-procedure care requirements, as the blood draw is a routine procedure with minimal risk. Patients may resume their normal activities immediately following the test. However, it is advisable for patients to follow up with their healthcare provider to discuss the results and any further steps that may be necessary based on the AMH levels obtained. This follow-up is crucial for understanding the implications of the test results on fertility planning and any potential treatment options that may be indicated.

Short Descr ASSAY ANTI-MULLERIAN HORM
Medium Descr ASSAY OF ANTI-MULLERIAN HORMONE
Long Descr Anti-mullerian hormone (AMH)
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) none
MUE 1
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
GZ Item or service expected to be denied as not reasonable and necessary
Date
Action
Notes
2024-01-01 Added Code Added.
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